The Miami Marlins saw their six game winning streak come to an end on Wednesday in a 4-3 loss to the Washington Nationals.

Brad Hand gave the Marlins another strong effort but it fell apart in the eighth inning. Three runs were charged to Hand but he only surrendered one himself. When he departed in the final frame, he left with two runners on and nobody out.

For the day, Hand went seven innings in which he allowed five hits and two walks. The inherited runners scored with A.J. Ramos on the mound. After retiring his first batter, Ramos gave up a sacrifice fly and then a two-run double.

Hand was tagged with the loss and is now 2-3 on the season but has tossed three quality starts in a row including this game.

The Marlins got on the board in the fourth inning when Jordany Valdespin hit his second home run of the season. Giancarlo Stanton hit a home run of his own in the ninth inning to trim the deficit to two runs. It was the 24th long ball of the season for the right-fielder.

After the blast, the Marlins continued to try and rally in the ninth. Adeiny Hechavarria doubled home a run to make it a one-run game. Jarrod Saltalamacchia pinch-hit next and walked to extend the game. Reed Johnson pinch-hit next and grounded out to end the game.

Miami will open a four-game series against the Cincinnati Reds on Thursday with Tom Koehler scheduled to start for the Marlins.