The entertainer — often referred to as the "Man of Many Voices" — died in his sleep early Friday morning. He was 52.
A family member who reportedly said Gans was having trouble breathing placed a call to 911 early Friday morning, but the impressionist died before help could arrive.
"Obviously everyone is in shock, I apologize, I want to give you more information but right now I have to tend to the family," Gans' longtime manager, Chip Lightman, told FOX5 in Las Vegas.
Gans, who was named "Las Vegas Entertainer of the Year" 11 times in a row, did not perform on Thursday night.
A former professional baseball player whose career was cut short by injury, Gans began performing in Las Vegas in 1996. Vegas mogul Steve Wynn hired Gans to work at the Mirage in 2000, where he performed until moving to Wynn's Encore resort in 2009.
Gans also had a role in the 1988 baseball film "Bull Durham," starring Kevin Costner.