Mick Mulvaney gained a key Senate supporter Wednesday, clearing his path to confirmation to be director of the Office of Management and Budget.
Sen. Susan Collins, R-Maine, had been withholding backing for Mulvaney, a conservative member of the House from South Carolina, but she said Wednesday that she would support him, giving him the support of a majority of senators, NBC News reported.
The Senate voted 51-49 to approve Mulvaney, with John McCain voting no. He'd said he opposes Mulvaney's desire to cut defense spending.
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The Senate was next set to debate the confirmation of Oklahoma Attorney General Scott Pruitt to lead the Environmental Protection Agency.
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Mulvaney's confirmation vote comes the day after fast food chain chief executive Andy Puzder became the first Cabinet nominee to withdraw as his support, even among Republicans, waned.