The hour-long show will air at 11 p.m. and replace the recently canceled sketch comedy show MadTV. The format of the show will feature a recurring panel of guests that will debate topics from politics to entertainment.
This is the second go-around for Sykes and the Fox network. She was the star of the short-lived sitcom Wanda At Large. The show had a nine-episode run in 2003. Sykes currently co-stars in The New Adventures of Old Christine on CBS with Julia Louis-Dreyfus.
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Sykes is entering unfamiliar territory in the highly competitive late-night circuit which is dominated by white male hosts. D.L. Hughley's show (D.L. Hughley Breaks The News) on CNN was just canceled and the same fate was suffered by David Alan Grier (Chocolate News) on Comedy Central.
Sykes will host the annual White House Correspondents' Association dinner later this month in Washington D.C.