Giancarlo Stanton hit a grand slam off Jamie Moyer in a five-run fourth inning, Mark Buehrle was dominant after a shaky first and the Miami Marlins stayed hot by beating the Colorado Rockies 7-4 on Monday night.

Austin Kearns tied a career-best with four hits for the Marlins, whose 15-5 record in May leads the majors.

Buehrle (4-4) worked 7 2-3 innings, giving up four runs and four hits in the first and one more hit the rest of the way. Heath Bell pitched the ninth for his sixth save in 10 chances.

Moyer (2-4) allowed nine hits and six runs in 3 2-3 innings in his debut at Marlins Park, the 50th big-league stadium in which the 49-year-old has appeared during his career.

Troy Tulowitzki hit a two-run home run and Michael Cuddyer had a two-run double for the Rockies.

Stanton wasn't even born when Moyer's career began in 1986. His first game against him was one to remember.

Miami's big fourth got going with one out, when Buehrle hit a soft double — the second of his career. He scored when Jose Reyes' single was bobbled by center fielder Dexter Fowler. Moyer nearly escaped further trouble, but walked Hanley Ramirez on a full count with two out, then walked Kearns to load the bases.

That brought up Stanton, who watched Moyer's 2-2 offering just miss — replays showed the inside pitch wasn't out of the zone by much, if at all.

Moyer's next pitch was 72 mph. It went out faster.

Stanton's ninth home run of the season and fourth career grand slam went an estimated 438 feet down the left field line, the impact of its collision with the video board over the left-field concourse temporarily knocking out a portion of the digital display. The Marlins had a 6-4 lead, and the crowd roared for nearly a minute before Stanton acknowledged their desire for a curtain call.

"I looked it up and 1986 was his debut and I wasn't even a thought at that moment," Stanton said. "I was born three years later."

Meanwhile, Buehrle was in a groove.

Buehrle got hit hard in the first, literally and figuratively. Jordan Pacheco lined a ball off Buehrle with one out, and scored along with Carlos Gonzalez two batters later when Cuddyer's double beat Kearns to the left-field wall. Tulowitzki followed with a homer to left that put the Rockies up 4-0 before Moyer even saw the mound.

Buehrle didn't give up another hit until Pacheco's two-out single in the eighth, tipping his cap to the crowd as he departed.

Moyer has pitched in more ballparks than anyone since at least 1921, and was 8-2 in the Marlins' former home, Sun Life Stadium. Marlins manager Ozzie Guillen — one of 11 current managers to bat against Moyer in their careers — went 4 for 22 against the lefty, and several members of the Miami coaching staff and front office also have faced him at one time or another.

"I don't remember much," Guillen said about his times against Moyer. "I know he went from very bad to very good to very old. ... I feel proud to know him."

Miami added an insurance run in the seventh, when Ramirez tripled and scored on Kearns' fourth hit.

NOTES: Stanton is the eighth player to hit a grand slam off Moyer, and Buehrle had never before batted twice in an inning until the fourth, according to STATS LLC. ... Miami RHP Ricky Nolasco (4-2, 4.10) is the Marlins' scheduled Tuesday starter against Colorado's Juan Nicasio (2-1, 4.37). ... Kearns stole second in the third inning, his first time swiping a bag since June 6, 2010. ... The Marlins hope to have 2B Omar Infante back Tuesday. Infante left the team Sunday to attend a family funeral in Venezuela. ... Pacheco extended his hitting streak to seven games.

For more recent Marlins coverage on NBCMiami.com, see here and here.