Randall Leal and Hany Mukhtar scored 10 minutes apart in the first half and Nashville beat Inter Miami 3-0 on Friday night in an all-expansion play-in round game.
Nashville advanced to face Toronto FC, last year's runner-up, on Tuesday night in East Hartford, Connecticut.
Leal scored the club's first playoff goal in the 14th minute with a shot from distance. Mukhtar sent Miami goalkeeper John McCarthy diving the wrong way on a penalty kick in the 24th.
Dax McCarty, who played in his 24 MLS playoff games, made it 3-0 in the 57th by dribbling it from midfield to the top of the 18-yard box and curling a shot inside the post. Goalkeeper Joe Willis made three saves.
There was an announced crowd of 3,240 at Nissan Stadium, home of the Tennessee Titans.